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Synaptic Hyper-Connectivity
Understanding how increased neural connections in autism lead to both enhanced pattern recognition and sensory challenges.
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References
- Tang, G., et al. (2014). Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron, 83(5), 1131-1143.
- Courchesne, E., et al. (2011). Neuron number and size in prefrontal cortex of children with autism. JAMA, 306(18), 2001-2010.
- Keown, C.L., et al. (2013). Local functional overconnectivity in posterior brain regions is associated with symptom severity in autism spectrum disorders. Cell Reports, 5(3), 567-572.
- Markram, K., & Markram, H. (2010). The intense world theory—a unifying theory of the neurobiology of autism. Frontiers in Human Neuroscience, 4, 224.